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The antibody against SLBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against SLBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-07411A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLBP |
| Target Synonyms | HBP; SLBP | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Jurkat, Mouse testis | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 125-223 of human SLBP (NP_006518.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | PADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSE | Uniprot ID | Q14493 |
Uniprot Id
Q14493
Target Species
Human
Target Name
SLBP
Target Full Name
Histone RNA hairpin-binding protein
Target Function
RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
SLBP family
Target Tissue Specificity
Widely expressed.
Target Synonyms
Hairpin binding protein histone; HBP; Histone binding protein; Histone RNA hairpin binding protein; Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; SLBP_HUMAN; Stem loop (histone) binding protein; Stem loop binding protein
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