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Rabbit anti-Human PCDH19 Polyclonal Antibody

The antibody against PCDH19 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 568-678 of human PCDH19 (NP_001171809.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08980A

The antibody against PCDH19 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 568-678 of human PCDH19 (NP_001171809.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08980A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePCDH19
Target SynonymsDEE9; EFMR; EIEE9; PCDH19FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293TApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 568-678 of human PCDH19 (NP_001171809.1).Target SpeciesHuman
Immunogen SequenceLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSUniprot IDQ8TAB3
Background Information
  • Uniprot Id

    Q8TAB3

  • Target Species

    Human

  • Target Name

    PCDH19

  • Target Full Name

    Protocadherin-19

  • Target Function

    Potential calcium-dependent cell-adhesion protein.

  • Target Involvement

    Epileptic encephalopathy, early infantile, 9 (EIEE9)

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.

  • Target Synonyms

    KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19

  • Target Background

    The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Mutations in this gene on human chromosome X are associated with sporadic infantile epileptic encephalopathy and to a female-restricted form of epilepsy (EFMR; also known as PCDH19RE). Multiple transcript variants encoding different isoforms have been found for this gene.

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