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Rabbit anti-Human CIZ1 Polyclonal Antibody

The antibody against CIZ1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09001A

The antibody against CIZ1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09001A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCIZ1
Target SynonymsNP94; LSFR1; ZNF356; CIZ1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490).Target SpeciesHuman
Immunogen SequencePGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNUniprot IDQ9ULV3
Background Information
  • Uniprot Id

    Q9ULV3

  • Target Species

    Human

  • Target Name

    CIZ1

  • Target Full Name

    Cip1-interacting zinc finger protein

  • Target Function

    May regulate the subcellular localization of CIP/WAF1.

  • Target Involvement

    Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk.

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    CDKI; CDKN1A-interacting zinc finger protein 1; Cip1-interacting zinc finger protein; CIZ1; CIZ1_HUMAN; cyclin dependent inhibitor 1A; LSFR1; Melanoma differentiation-associated protein; NP94; Nuclear protein NP94; OPHN3; P21; Zinc finger protein 356; ZNF356

  • Target Background

    The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene.

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