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The antibody against XPNPEP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against XPNPEP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09020A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | XPNPEP2 |
| Target Synonyms | APP2; AEACEI; XPNPEP2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, 293T, A-549, HepG2, HT-29, Mouse small intestine, Rat kidney, SW480 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43895 | Immunogen Sequence |
Uniprot Id
O43895
Target Species
Human
Target Name
XPNPEP2
Target Full Name
Xaa-Pro aminopeptidase 2
Target Function
Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Target Involvement
Angioedema induced by ACE inhibitors (AEACEI)
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Peptidase M24B family
Target Tissue Specificity
Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary.
Target Synonyms
Aminoacylproline aminopeptidase; mAmP; mAPP; Membrane bound aminopeptidase P; Membrane bound AmP; Membrane bound APP; Membrane-bound aminopeptidase P; Membrane-bound AmP; Membrane-bound APP; RP23-351G20.1; RP4-753P9.2; X Pro aminopeptidase 2; X prolyl aminopeptidase (aminopeptidase P) 2, membrane bound; X-Pro aminopeptidase 2; Xaa Pro aminopeptidase 2; Xaa-Pro aminopeptidase 2; XPNPEP2; XPP2_HUMAN
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