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The antibody against CR2/CD21 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human CR2/CD21 (NP_001006659.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against CR2/CD21 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human CR2/CD21 (NP_001006659.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-09032A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CR2/CD21 |
| Target Synonyms | CR; C3DR; CD21; CVID7; SLEB9; CR2/CD21 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Daudi, K-562, Raji | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human CR2/CD21 (NP_001006659.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P20023 | Immunogen Sequence |
Uniprot Id
P20023
Target Species
Human
Target Name
CR2
Target Full Name
Complement receptor type 2
Target Function
Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU. Participates in B lymphocytes activation.; (Microbial infection) Acts as a receptor for Epstein-Barr virus.
Target Involvement
Systemic lupus erythematosus 9 (SLEB9); Immunodeficiency, common variable, 7 (CVID7)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Receptors of complement activation (RCA) family
Target Tissue Specificity
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Target Synonyms
C3DR; CD 21; CD21; Complement C3d receptor 2; Complement C3d receptor; Complement component (3d/Epstein Barr virus) receptor 2; Complement receptor type 2; CR; Cr2; CR2_HUMAN; CVID7; EBV receptor; EBV-R; Epstein Barr virus receptor; Epstein-Barr virus receptor; EVBR; SLEB9
Target Background
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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