Rabbit anti-Human CALCRL Polyclonal Antibody

The antibody against CALCRL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 392-461 of human CALCRL (NP_005786.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09231A

Number

Cat.No	ADA-09231A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CALCRL
Target Synonyms	CRLR; CGRPR; LMPHM8; CALCRL	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse heart, Mouse brain	Application	ELISA, WB

Cat.No

ADA-09231A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CALCRL

Target Synonyms

CRLR; CGRPR; LMPHM8; CALCRL

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse heart, Mouse brain

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 392-461 of human CALCRL (NP_005786.1).	Target Species	Human
Immunogen Sequence	QAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN	Uniprot ID	Q16602

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 392-461 of human CALCRL (NP_005786.1).

Target Species

Human

Immunogen Sequence

QAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN

Uniprot ID

Q16602

Background Information

Uniprot Id

Q16602
Target Species

Human
Target Name

CALCRL
Target Full Name

Calcitonin gene-related peptide type 1 receptor
Target Function

Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family
Target Tissue Specificity

Predominantly expressed in the lung and heart.
Target Synonyms

CALCRL; CGRPR; Calcitonin gene-related peptide type 1 receptor; CGRP type 1 receptor; Calcitonin receptor-like receptor
Target Background

Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema.

Rabbit anti-Human CALCRL Polyclonal Antibody

Specifications

Immunogen Information

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