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The antibody against PPP6R3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PPP6R3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09251A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP6R3 |
| Target Synonyms | SAPL; PP6R3; SAPLa; SAPS3; SAP190; C11orf23; PPP6R3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung, Mouse thymus, Rat lung, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PPP6R3 (NP_060782.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5H9R7 | Immunogen Sequence |
Uniprot Id
Q5H9R7
Target Species
Human
Target Name
PPP6R3
Target Full Name
Serine/threonine-protein phosphatase 6 regulatory subunit 3
Target Function
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
SAPS family
Target Tissue Specificity
Expressed in skeletal muscle, placenta, heart, pancreas, testis, brain, lung, liver, kidney, spleen, thymus, prostate, small intestine, colon and leukocytes.
Target Synonyms
C11orf23 ; Chromosome 11 open reading frame 23 ; KIAA1558; PP6R3 ; PP6R3_HUMAN; PPP6R3; Protein phosphatase 6 regulatory subunit 3 ; SAP190 ; SAPL ; SAPLa; SAPS domain family member 3; SAPS domain family; member 3; Serine/threonine-protein phosphatase 6 regulatory subunit 3; Sporulation induced transcript 4 associated protein SAPL; Sporulation-induced transcript 4-associated protein SAPL
Target Background
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).
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