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The antibody against FAM173B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FAM173B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09332A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FAM173B |
| Target Synonyms | JS-2; FAM173B; hFAM173B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, Rat brain, A-549, BT-474, HL-60, Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6P4H8 | Immunogen Sequence |
Uniprot Id
Q6P4H8
Target Species
Human
Target Name
ATPSCKMT
Target Full Name
ATP synthase subunit C lysine N-methyltransferase
Target Function
Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. Promotes chronic pain. Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS) and on the engagement of spinal cord microglia.
Target Subcellular Location
Mitochondrion membrane; Single-pass membrane protein.
Target Protein Families
FAM173 family
Target Tissue Specificity
Ubiquitously expressed.
Target Research Area
Others
Target Synonyms
ATPSCKMT; FAM173B; ATP synthase subunit C lysine N-methyltransferase; Protein N-lysine methyltransferase FAM173B; hFAM173B
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