Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against MAT1A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_000420.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MAT1A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_000420.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
Western blot analysis of Rat liver, using MAT1A Rabbit pAb at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
| Cat.No | ADA-09448A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAT1A |
| Target Synonyms | MAT; SAMS; MATA1; SAMS1; MAT1A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_000420.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q00266 | Immunogen Sequence |
Uniprot Id
Q00266
Target Species
Human
Target Name
MAT1A
Target Full Name
S-adenosylmethionine synthase isoform type-1
Target Function
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Target Involvement
Methionine adenosyltransferase deficiency (MATD)
Target Protein Families
AdoMet synthase family
Target Tissue Specificity
Expressed in liver.
Target Research Area
Signal Transduction
Target Synonyms
MAT1A; AMS1; MATA1S-adenosylmethionine synthase isoform type-1; AdoMet synthase 1; EC 2.5.1.6; Methionine adenosyltransferase 1; MAT 1; Methionine adenosyltransferase I/III; MAT-I/III
Target Background
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
