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The antibody against CHD7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CHD7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09547A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHD7 |
| Target Synonyms | CRG; HH5; IS3; KAL5; CHD7 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9P2D1 | Immunogen Sequence |
Uniprot Id
Q9P2D1
Target Species
Human
Target Name
CHD7
Target Full Name
Chromodomain-helicase-DNA-binding protein 7
Target Function
Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production.
Target Involvement
CHARGE syndrome (CHARGES); Idiopathic scoliosis 3 (IS3); Hypogonadotropic hypogonadism 5 with or without anosmia (HH5)
Target Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 3]: Nucleus, nucleolus.
Target Protein Families
SNF2/RAD54 helicase family
Target Tissue Specificity
Widely expressed in fetal and adult tissues.
Target Synonyms
ATP-dependent helicase CHD7; ATP-dependent helicase chromodomain helicase DNA binding protein 7; CHD-7; Chd7; CHD7_HUMAN; Chromodomain helicase DNA binding protein 7; chromodomain helicase DNA binding protein 7 isoform CRA_e; Chromodomain-helicase-DNA-binding protein 7; FLJ20357; FLJ20361; HH5; IS3; KAL5; KIAA1416
Target Background
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene.
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