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The antibody against PDYN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 21-254 of human PDYN (NP_077722.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against PDYN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 21-254 of human PDYN (NP_077722.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09641A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDYN |
| Target Synonyms | ADCA; PENKB; SCA23; PDYN | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Mouse pancreas, U-251MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 21-254 of human PDYN (NP_077722.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P01213 | Immunogen Sequence |
Uniprot Id
P01213
Target Species
Human
Target Name
PDYN
Target Full Name
Proenkephalin-B
Target Function
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.; Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.; Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
Target Involvement
Spinocerebellar ataxia 23 (SCA23)
Target Subcellular Location
Secreted.
Target Protein Families
Opioid neuropeptide precursor family
Target Synonyms
ADCA; Alpha neoendorphin; Beta neoendorphin; Beta-neoendorphin-dynorphin; Big Dyn; Big dynorphin; Dyn; Dyn-A17; Dyn-B; Dynorphin A; Dynorphin A(1-13); Dynorphin A(1-17); Dynorphin A(1-8); Dynorphin B; Dynorphin B(1-13); Dynorphin B-29; Enkephalin B; Leu enkephalin; Leumorphin; Neoendorphin dynorphin enkephalin prepropeptide; PDYN; PDYN_HUMAN; PENKB; Preprodynorphin; Preproenkephalin B; Prodynorphin; Proenkephalin B; Rimorphin; SCA23
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