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The antibody against ADAMTSL4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 795-1074 of human ADAMTSL4 (NP_061905.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ADAMTSL4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 795-1074 of human ADAMTSL4 (NP_061905.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09733A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADAMTSL4 |
| Target Synonyms | TSRC1; ECTOL2; ADAMTSL-4; ADAMTSL4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, Mouse brain, Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 795-1074 of human ADAMTSL4 (NP_061905.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6UY14 | Immunogen Sequence |
Uniprot Id
Q6UY14
Target Species
Human
Target Name
ADAMTSL4
Target Full Name
ADAMTS-like protein 4
Target Function
Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.
Target Involvement
Ectopia lentis 2, isolated, autosomal recessive (ECTOL2); Ectopia lentis et pupillae (ECTOLP)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix. Note=Colocalizes with FMN1 microfibrils in the eye ECM.
Target Tissue Specificity
Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta. Weaker expression in bone marrow, brain tissue, kidney and pancreas. Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lun
Target Synonyms
ADAMTSL4; TSRC1; PP1396; UNQ2803/PRO34012ADAMTS-like protein 4; ADAMTSL-4; Thrombospondin repeat-containing protein 1
Target Background
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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