Rabbit anti-Human ENTPD1/CD39 Polyclonal Antibody

The antibody against ENTPD1/CD39 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ENTPD1/CD39 (NP_001157655.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-09790A

Number

Cat.No	ADA-09790A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ENTPD1/CD39
Target Synonyms	CD39; SPG64; ATPDase; NTPDase-1; ENTPD1/CD39	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse spleen, Rat lung	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-09790A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ENTPD1/CD39

Target Synonyms

CD39; SPG64; ATPDase; NTPDase-1; ENTPD1/CD39

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse spleen, Rat lung

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ENTPD1/CD39 (NP_001157655.1).	Target Species	Human
Immunogen Sequence	MESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQG	Uniprot ID	P49961

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ENTPD1/CD39 (NP_001157655.1).

Target Species

Human

Immunogen Sequence

MESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQG

Uniprot ID

P49961

Background Information

Uniprot Id

P49961
Target Species

Human
Target Name

ENTPD1
Target Full Name

Ectonucleoside triphosphate diphosphohydrolase 1
Target Function

In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
Target Involvement

Spastic paraplegia 64, autosomal recessive (SPG64)
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

GDA1/CD39 NTPase family
Target Tissue Specificity

Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
Target Synonyms

ATPDase; CD 39; CD39; CD39 antigen; DKFZp686D194; DKFZp686I093; Ecto apyrase; Ecto ATP diphosphohydrolase; Ecto-apyrase; Ecto-ATP diphosphohydrolase 1; Ecto-ATPase 1; Ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTP1_HUMAN; ENTPD 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase1; SPG64
Target Background

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human ENTPD1/CD39 Polyclonal Antibody

Specifications

Immunogen Information

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