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Rabbit anti-Human SLC28A2 Polyclonal Antibody

The antibody against SLC28A2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC28A2 (NP_004203.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10009A

The antibody against SLC28A2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC28A2 (NP_004203.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-10009A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC28A2
Target SynonymsCNT2; HCNT2; SPNT1; HsT17153; SLC28A2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Rat heart, 293T, BxPC-3, HepG2, HT-29, Mouse spleen, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC28A2 (NP_004203.2).Target SpeciesHuman
Immunogen SequenceGAFIAFGVDASSLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLATNVAANLIAFLAVLAFINAALSWLGELVDIUniprot IDO43868
Background Information
  • Uniprot Id

    O43868

  • Target Species

    Human

  • Target Name

    SLC28A2

  • Target Full Name

    Sodium/nucleoside cotransporter 2

  • Target Function

    Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Concentrative nucleoside transporter (CNT) (TC 2.A.41) family

  • Target Tissue Specificity

    Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.

  • Target Synonyms

    SLC28A2; CNT2; Sodium/nucleoside cotransporter 2; Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier family 28 member 2

  • Target Background

    Enables neurotransmitter transmembrane transporter activity and nucleoside transmembrane transporter activity. Involved in several processes, including nucleoside transport; purine nucleobase transmembrane transport; and pyrimidine-containing compound transmembrane transport. Predicted to be located in membrane. Predicted to be part of brush border membrane; coated vesicle; and vesicle membrane. Predicted to be integral component of plasma membrane.

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