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The antibody against TBRG4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 382-631 of human TBRG4 (NP_004740.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TBRG4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 382-631 of human TBRG4 (NP_004740.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
Western blot analysis of HepG2, using TBRG4 Rabbit pAb at 1:2000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
| Cat.No | ADA-10059A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBRG4 |
| Target Synonyms | CPR2; FASTKD4; TBRG4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 382-631 of human TBRG4 (NP_004740.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q969Z0 | Immunogen Sequence |
Uniprot Id
Q969Z0
Target Species
Human
Target Name
TBRG4
Target Full Name
FAST kinase domain-containing protein 4
Target Function
Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
FAST kinase family
Target Tissue Specificity
Ubiquitously expressed. Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in smooth muscle.
Target Synonyms
Cell cycle progression protein 2; Cell cycle progression restoration protein 2; CPR2; FAST kinase domain containing protein 4 ; FAST kinase domain-containing protein 4; FASTKD4; KIAA0948; Protein TBRG4; Tbrg4; TBRG4_HUMAN; Transforming growth factor beta regulator 4
Target Background
Enables RNA binding activity. Involved in mitochondrial mRNA processing and regulation of mitochondrial mRNA stability. Located in mitochondrial matrix.
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