Rabbit anti-Human PLD1 Polyclonal Antibody

The antibody against PLD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_001123553.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10145A

Number

Cat.No	ADA-10145A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PLD1
Target Synonyms	CVDD; CVDP1; PLD1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Application	ELISA, WB

Cat.No

ADA-10145A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PLD1

Target Synonyms

CVDD; CVDP1; PLD1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_001123553.1).	Target Species	Human
Immunogen Sequence	NINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT	Uniprot ID	Q13393

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_001123553.1).

Target Species

Human

Immunogen Sequence

NINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT

Uniprot ID

Q13393

Background Information

Uniprot Id

Q13393
Target Species

Human
Target Name

PLD1
Target Full Name

Phospholipase D1
Target Function

Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
Target Involvement

Cardiac valvular defect, developmental (CVDD)
Target Subcellular Location

Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid-anchor; Cytoplasmic side.
Target Protein Families

Phospholipase D family
Target Tissue Specificity

Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
Target Synonyms

Choline phosphatase 1; hPLD1; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; PLD 1; PLD1; PLD1_HUMAN
Target Background

This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.

Rabbit anti-Human PLD1 Polyclonal Antibody

Specifications

Immunogen Information

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