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Rabbit anti-Human GANAB Polyclonal Antibody

The antibody against GANAB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-10266A

The antibody against GANAB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-10266A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGANAB
Target SynonymsG2AN; GIIA; PKD3; GLUII; GANABFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Rat brain, HepG2, Mouse brain, Mouse liver, Raji, U-87MGApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_001265123.1).Target SpeciesHuman
Uniprot IDQ14697Immunogen Sequence
Background Information
  • Uniprot Id

    Q14697

  • Target Species

    Human

  • Target Name

    GANAB

  • Target Full Name

    Neutral alpha-glucosidase AB

  • Target Function

    Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia.

  • Target Involvement

    Polycystic kidney disease 3 (PKD3)

  • Target Subcellular Location

    Endoplasmic reticulum. Golgi apparatus. Melanosome.

  • Target Protein Families

    Glycosyl hydrolase 31 family

  • Target Tissue Specificity

    Detected in placenta. Isoform 1 and isoform 2 are expressed in the kidney and liver.

  • Target Synonyms

    Alpha glucosidase II alpha subunit; Alpha-glucosidase 2; G2AN; GANAB; GANAB_HUMAN; Glu II; Glucosidase alpha neutral AB; Glucosidase II alpha; Glucosidase II subunit alpha; GluII; KIAA0088; Neutral alpha glucosidase AB; Neutral alpha glucosidase AB precursor ; Neutral alpha-glucosidase AB

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