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The antibody against CD66b/CEACAM8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CD66b/CEACAM8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
Immunofluorescence analysis of Jurkat cells using CD66b/CEACAM8 Rabbit pAb at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
| Cat.No | ADA-10453A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD66b/CEACAM8 |
| Target Synonyms | CD67; CGM6; CD66b; NCA-95; CD66b/CEACAM8 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CD66b/CEACAM8 (NP_001807.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P31997 | Immunogen Sequence |
Uniprot Id
P31997
Target Species
Human
Target Name
CEACAM8
Target Full Name
Cell adhesion molecule CEACAM8
Target Function
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
Target Protein Families
Immunoglobulin superfamily, CEA family
Target Tissue Specificity
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Target Research Area
Immunology
Target Synonyms
Carcinoembryonic antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic antigen related cell adhesion molecule 8; Carcinoembryonic antigen-related cell adhesion molecule 8; CD 66b; CD 67; CD66b; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CEAM8_HUMAN; CGM 6; CGM6; NCA 95; NCA95; Non-specific cross-reacting antigen NCA-95; Nonspecific cross reacting antigen NCA 95; Nonspecific cross reacting antigen NCA95
Target Background
Enables protein heterodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell surface and extracellular space. Biomarker of severe acute respiratory syndrome.
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