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The antibody against SCG3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SCG3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10976A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCG3 |
| Target Synonyms | SGIII; SCG3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat brain, Rat heart, 22Rv1, HepG2, Mouse brain, Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WXD2 | Immunogen Sequence |
Uniprot Id
Q8WXD2
Target Species
Human
Target Name
SCG3
Target Full Name
Secretogranin-3
Target Function
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted.
Target Tissue Specificity
Expressed in brain, heart, kidney, liver and skeletal muscle.
Target Synonyms
1B1075; AI385542; Chgd; SCG3; SCG3_HUMAN; Secretogranin III; Secretogranin-3; SGCG; SgIII
Target Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
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