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The antibody against PNMT was raised in rabbit using the Recombinant Human Phenylethanolamine N-methyltransferase protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PNMT was raised in rabbit using the Recombinant Human Phenylethanolamine N-methyltransferase protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-07705A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNMT |
| Target Synonyms | Noradrenaline N-methyltransferase antibody; PENT antibody; Phenylethanolamine N-methyltransferase antibody; PNMT antibody; PNMT_HUMAN antibody; PNMTase antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phenylethanolamine N-methyltransferase protein (1-176AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P11086 |
Uniprot Id
P11086
Target Species
Human
Target Name
PNMT
Target Full Name
Phenylethanolamine N-methyltransferase
Target Function
Converts noradrenaline to adrenaline.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family
Target Synonyms
Noradrenaline N-methyltransferase; PENT; Phenylethanolamine N-methyltransferase; PNMT; PNMT_HUMAN; PNMTase
Target Background
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
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