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The recombinant antibody against ACO2 was produced using a synthesized peptide derived from human Aconitase 2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC.
The recombinant antibody against ACO2 was produced using a synthesized peptide derived from human Aconitase 2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC.
$350.00
| Cat.No | ADC-56798A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | ACO2 | Target Synonyms | ACO2, Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human Aconitase 2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99798 |
Uniprot Id
Q99798
Target Species
Human
Target Name
ACO2
Target Full Name
Aconitate hydratase, mitochondrial
Target Function
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Target Involvement
Infantile cerebellar-retinal degeneration (ICRD); Optic atrophy 9 (OPA9)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Aconitase/IPM isomerase family
Target Research Area
Metabolism
Target Synonyms
ACO 2; ACO2; ACON_HUMAN; aconitase 2; Aconitase 2 mitochondrial; Aconitase; Aconitase2; Aconitate hydratase; Aconitate hydratase mitochondrial; ACONM; Citrate hydro lyase; Citrate hydro-lyase; ICRD; mitochondrial
Target Background
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
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