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The recombinant antibody against ALPP was produced using a synthesized peptide derived from Human ALPP as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, FC.
The recombinant antibody against ALPP was produced using a synthesized peptide derived from Human ALPP as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, FC.
$350.00
Western Blot | Positive WB detected in: PC-3 whole cell lysate,Hela whole cell lysate | All lanes: Placental alkaline phosphatase (PLAP) antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 70 kDa | Observed band size: 70 kDa
| Cat.No | ADC-56523A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | ALPP | Target Synonyms | Alkaline phosphatase, ALPP, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1), PLAP |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human ALPP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P05187 |
Uniprot Id
P05187
Target Species
Human
Target Name
ALPP
Target Full Name
Alkaline phosphatase, placental type
Target Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Alkaline phosphatase family
Target Tissue Specificity
Detected in placenta (at protein level).
Target Research Area
Tags & Cell Markers
Target Synonyms
ALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1
Target Background
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
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