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The antibody against DME was raised in rabbit using the Recombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against DME was raised in rabbit using the Recombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-10229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DME |
| Target Synonyms | DME antibody; At5g04560/At5g04570/At5g04580 antibody; T32M21.160/T32M21.170/T32M21.180Transcriptional activator DEMETER antibody; EC 3.2.2.- antibody; DNA glycosylase-related protein DME antibody | Form | Liquid |
| Species Reactivity | Arabidopsis thaliana | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA) | Target Species | Arabidopsis thaliana (Mouse-ear cress) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8LK56 |
Uniprot Id
Q8LK56
Target Species
Arabidopsis thaliana
Target Name
DME
Target Function
Transcriptional activator involved in gene imprinting. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism. Allows the expression of the maternal copy of the imprinted MEA gene before fertilization, possibly by antagonizing or suppressing DNA methylation on target promoter. Probably acts by nicking the MEA promoter. Required for stable reproducible patterns of floral and vegetative development.
Target Subcellular Location
Nucleus.
Target Protein Families
DNA glycosylase family, DEMETER subfamily
Target Tissue Specificity
Mainly expressed in immature flower buds, then decreases as the flower matures. Expressed in the ovule carpels, but not expressed in pollen stamens. Expressed in developing and mature ovules (stages 12-14), then strongly decreases after fertilization.
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