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Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DME Polyclonal Antibody, HRP conjugated

The antibody against DME was raised in rabbit using the Recombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-10229A

The antibody against DME was raised in rabbit using the Recombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-10229A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDME
Target SynonymsDME antibody; At5g04560/At5g04570/At5g04580 antibody; T32M21.160/T32M21.170/T32M21.180Transcriptional activator DEMETER antibody; EC 3.2.2.- antibody; DNA glycosylase-related protein DME antibodyFormLiquid
Species ReactivityArabidopsis thalianaIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateHRP conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Arabidopsis thaliana Transcriptional activator DEMETER protein (1-320AA)Target SpeciesArabidopsis thaliana (Mouse-ear cress)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8LK56
Background Information
  • Uniprot Id

    Q8LK56

  • Target Species

    Arabidopsis thaliana

  • Target Name

    DME

  • Target Function

    Transcriptional activator involved in gene imprinting. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism. Allows the expression of the maternal copy of the imprinted MEA gene before fertilization, possibly by antagonizing or suppressing DNA methylation on target promoter. Probably acts by nicking the MEA promoter. Required for stable reproducible patterns of floral and vegetative development.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    DNA glycosylase family, DEMETER subfamily

  • Target Tissue Specificity

    Mainly expressed in immature flower buds, then decreases as the flower matures. Expressed in the ovule carpels, but not expressed in pollen stamens. Expressed in developing and mature ovules (stages 12-14), then strongly decreases after fertilization.

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