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The antibody against Snaclec rhodocytin subunit alpha was raised in rabbit using the Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against Snaclec rhodocytin subunit alpha was raised in rabbit using the Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-09207A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Snaclec rhodocytin subunit alpha |
| Target Synonyms | antibody; Snaclec rhodocytin subunit alpha antibody; Aggretin alpha chain antibody; Rhodoaggretin subunit alpha antibody | Form | Liquid |
| Species Reactivity | Calloselasma rhodostoma | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA) | Target Species | Calloselasma rhodostoma |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9I841 |
Uniprot Id
Q9I841
Target Species
Calloselasma rhodostoma
Target Function
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
Target Subcellular Location
Secreted.
Target Protein Families
Snaclec family
Target Tissue Specificity
Expressed by the venom gland.
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