Rabbit anti- CAPRIN2 Polyclonal Antibody

The antibody against CAPRIN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 88-329 of CAPRIN2 (NP_001002259.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06715A

Number

Cat.No	ADA-06715A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CAPRIN2
Target Synonyms	EEG1; EEG-1; C1QDC1; RNG140; CAPRIN2	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	C6, 293T, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-06715A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CAPRIN2

Target Synonyms

EEG1; EEG-1; C1QDC1; RNG140; CAPRIN2

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

C6, 293T, SH-SY5Y

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 88-329 of CAPRIN2 (NP_001002259.1).	Uniprot ID	Q6IMN6
Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 88-329 of CAPRIN2 (NP_001002259.1).

Uniprot ID

Q6IMN6

Immunogen Sequence

Background Information

Uniprot Id

Q6IMN6
Target Species

Human
Target Name

CAPRIN2
Target Full Name

Caprin-2
Target Function

Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis.
Target Subcellular Location

[Isoform 1]: Cytoplasm.; [Isoform 2]: Mitochondrion. Cytoplasm. Note=Expressed throughout the cytoplasm.; [Isoform 5]: Mitochondrion. Note=Colocalizes with aggregated mitochondria.; Cell membrane; Peripheral membrane protein.
Target Protein Families

Caprin family
Target Tissue Specificity

Detected in all tissues tested with highest levels of expression in brain and spleen.
Target Synonyms

C1q domain-containing protein 1; C1QDC1; CAPR2_HUMAN; Caprin family member 2; Caprin-2; caprin2; Cytoplasmic activation/proliferation-associated protein 2; EEG 1; EEG1; Gastric cancer multidrug resistance-associated protein; KIAA1873; Protein EEG-1; RNA granule protein 140; RNG140
Target Background

The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene.

Rabbit anti- CAPRIN2 Polyclonal Antibody

Specifications

Immunogen Information

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