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The antibody against gL was raised in rabbit using the Recombinant Epstein-Barr virus gL protein (23-137aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against gL was raised in rabbit using the Recombinant Epstein-Barr virus gL protein (23-137aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: gL Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 43 kDa | Observed band size: 43 kDa
| Cat.No | ADC-55279A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | gL |
| Target Synonyms | Envelope glycoprotein L (gL), gL | Form | Liquid |
| Species Reactivity | Epstein-Barr virus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Immunogen Description | Recombinant Epstein-Barr virus gL protein (23-137aa) | Target Species | Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P03212 |
Uniprot Id
P03212
Target Species
Epstein-Barr virus
Target Name
GL
Target Function
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL. The heterodimer gH/gL targets also host EPHA2 to promote viral entry.
Target Subcellular Location
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans-Golgi network.
Target Protein Families
Herpesviridae glycoprotein L family
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