Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against tir was raised in rabbit using the Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against tir was raised in rabbit using the Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-12063A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | tir |
| Target Synonyms | tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody | Form | Liquid |
| Species Reactivity | Escherichia coli O157:H7 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA) | Target Species | Escherichia coli O157:H7 (strain TW14359 / EHEC) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | C6UYL8 |
Uniprot Id
C6UYL8
Target Species
E.coli
Target Name
TIR
Target Function
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion.
Target Subcellular Location
Secreted. Host cell membrane; Multi-pass membrane protein.
Target Protein Families
Tir receptor family
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
