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The recombinant antibody against FLI1 was produced using a synthesized peptide derived from human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The recombinant antibody against FLI1 was produced using a synthesized peptide derived from human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
$350.00
Western Blot | Positive WB detected in: A549 whole cell lysate, U-251 whole cell lysate, Hela whole cell lysate | All lanes: FLI1 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 51, 44, 48, 30 kDa | Observed band size: 51 kDa
| Cat.No | ADC-56833A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | FLI1 | Target Synonyms | FLI1, Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB) |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human FLI1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q01543 |
Uniprot Id
Q01543
Target Species
Human
Target Name
FLI1
Target Full Name
Friend leukemia integration 1 transcription factor
Target Function
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Target Involvement
Ewing sarcoma (ES); Bleeding disorder, platelet-type 21 (BDPLT21)
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Research Area
Cancer
Target Synonyms
(Proto-oncogene Fli-1)(Transcription factor ERGB)
Target Background
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
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