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The recombinant antibody against GJB2 was produced using the Recombinant Human GJB2 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
The recombinant antibody against GJB2 was produced using the Recombinant Human GJB2 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
$350.00
| Cat.No | ADC-56401A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | GJB2 | Form | Liquid |
| Species Reactivity | Human | Isotype | Mouse IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, FC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GJB2 protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P29033 |
Uniprot Id
P29033
Target Species
Human
Target Name
GJB2
Target Full Name
Gap junction beta-2 protein
Target Function
Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
Target Involvement
Deafness, autosomal recessive, 1A (DFNB1A); Deafness, autosomal dominant, 3A (DFNA3A); Vohwinkel syndrome (VOWNKL); Keratoderma, palmoplantar, with deafness (PPKDFN); Keratitis-ichthyosis-deafness syndrome (KID syndrome); Bart-Pumphrey syndrome (BPS); Ichthyosis hystrix-like with deafness syndrome (HID syndrome)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Target Protein Families
Connexin family, Beta-type (group I) subfamily
Target Synonyms
GJB2; Gap junction beta-2 protein; Connexin-26; Cx26
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