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The antibody against ABCA5 was raised in rabbit using the Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ABCA5 was raised in rabbit using the Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using ABCA5 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using ABCA5 Antibody at dilution of 1:1002
| Cat.No | ADC-11726A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABCA5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WWZ7 |
Uniprot Id
Q8WWZ7
Target Species
Human
Target Name
ABCA5
Target Full Name
Cholesterol transporter ABCA5
Target Function
Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes.
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell membrane.
Target Protein Families
ABC transporter superfamily, ABCA family
Target Tissue Specificity
Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. Expressed in both the epithelial and mesenchymal compartments, present within the outer root sheath (ORS) of the hair follicle as well as dermal sheath. Expre
Target Synonyms
ABC13; ABCA5; ABCA5_HUMAN; ATP binding cassette sub family A (ABC1) member 5; ATP binding cassette A5; ATP binding cassette sub family A member 5; ATP-binding cassette sub-family A member 5; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; KIAA1888
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