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Rabbit anti-Human ABCA6 Polyclonal Antibody

The antibody against ABCA6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 690-828 of human ABCA6 (NP_525023.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07858A

The antibody against ABCA6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 690-828 of human ABCA6 (NP_525023.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07858A ClonalityPolyclonal
Host SpeciesRabbitTarget NameABCA6
Target SynonymsEST155051; ABCA6FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 690-828 of human ABCA6 (NP_525023.2).Target SpeciesHuman
Immunogen SequenceRLKCAGSSMFLKRRWGLGYHLSLHRNEICNPEQITSFITHHIPDAKLKTENKEKLVYTLPLERTNTFPDLFSDLDKCSDQGVTGYDISMSTLNEVFMKLEGQSTIEQDFEQVEMIRDSESLNEMELAHSSFSEMQTAVSUniprot IDQ8N139
Background Information
  • Uniprot Id

    Q8N139

  • Target Species

    Human

  • Target Name

    ABCA6

  • Target Full Name

    ATP-binding cassette sub-family A member 6

  • Target Function

    Probable transporter which may play a role in macrophage lipid transport and homeostasis.

  • Target Subcellular Location

    Golgi apparatus membrane; Multi-pass membrane protein.

  • Target Protein Families

    ABC transporter superfamily, ABCA family

  • Target Tissue Specificity

    Widely expressed with higher expression in liver.

  • Target Synonyms

    ABC transporter ABCA6; ABCA 6; ABCA6; ABCA6_HUMAN; ATP binding cassette A6; ATP binding cassette sub family A (ABC1) member 6; ATP binding cassette sub family A member 6; ATP-binding cassette sub-family A member 6; EST155051; FLJ43498

  • Target Background

    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.

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