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The antibody against ABCB5 was raised in rabbit using the Recombinant Human ATP-binding cassette sub-family B member 5 protein (547-760AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ABCB5 was raised in rabbit using the Recombinant Human ATP-binding cassette sub-family B member 5 protein (547-760AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver cancer using ABCB5 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using ABCB5 Antibody at dilution of 1:1002
Immunofluorescent analysis of A431 cells using ABCB5 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-22786A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABCB5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human ATP-binding cassette sub-family B member 5 protein (547-760AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q2M3G0 |
Uniprot Id
Q2M3G0
Target Species
Human
Target Name
ABCB5
Target Full Name
ATP-binding cassette sub-family B member 5
Target Function
Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Target Tissue Specificity
Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expr
Target Synonyms
ABCB 5; ABCB5; ABCB5 P-gp; ABCB5_HUMAN; ABCB5alpha; ABCB5beta; ATP binding cassette protein; ATP binding cassette sub family B (MDR/TAP) member 5; ATP binding cassette sub family B member 5; ATP-binding cassette sub-family B member 5; EST422562; P glycoprotein ABCB5; P-glycoprotein ABCB5
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