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The antibody against ACOT2 was raised in rabbit using the Synthesized peptide derived from internal of Human ACOT2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against ACOT2 was raised in rabbit using the Synthesized peptide derived from internal of Human ACOT2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from Jurkat cells and HuvEc cells, using ACOT2 antibody.
| Cat.No | ADC-41520A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACOT2 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ACOT2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49753 |
Uniprot Id
P49753
Target Species
Human
Target Name
ACOT2
Target Full Name
Acyl-coenzyme A thioesterase 2, mitochondrial
Target Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.
Target Subcellular Location
Mitochondrion.
Target Protein Families
C/M/P thioester hydrolase family
Target Tissue Specificity
Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.
Target Synonyms
ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128
Target Background
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.
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