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The antibody against ACP5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-232 of human ACP5 (NP_001602.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ACP5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-232 of human ACP5 (NP_001602.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07221A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACP5 |
| Target Synonyms | HPAP; TRAP; TRAcP; TRACP5a; TRACP5b; TrATPase; ACP5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 22-232 of human ACP5 (NP_001602.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P13686 | Immunogen Sequence |
Uniprot Id
P13686
Target Species
Human
Target Name
ACP5
Target Full Name
Tartrate-resistant acid phosphatase type 5
Target Function
Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Target Involvement
Spondyloenchondrodysplasia with immune dysregulation (SPENCDI)
Target Subcellular Location
Lysosome.
Target Protein Families
Metallophosphoesterase superfamily, Purple acid phosphatase family
Target Research Area
Metabolism
Target Synonyms
ype 5 acid phosphatase; Acid phosphatase 5 tartrate resistant; Acid phosphatase 5; tartrate resistant; ACP5; EC 3.1.3.2; MGC117378; PPA5_HUMAN; serum band 5 tartrate-resistant acid phosphatase; SPENCDI; T5ap; Tartrate resistant acid ATPase; Tartrate resistant acid phosphatase type 5; Tartrate resistant acid phosphatase type 5 precursor; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; TR AP; TR-AP; TRACP 5; TRAP; TrATPase; Type 5 acid phosphatase
Target Background
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
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