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The antibody against ACTR3B was raised in rabbit using the Recombinant Human Actin-related protein 3B protein (189-418AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ACTR3B was raised in rabbit using the Recombinant Human Actin-related protein 3B protein (189-418AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using ACTR3B Antibody at dilution of 1:1002
| Cat.No | ADC-44434A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACTR3B |
| Target Synonyms | ACTR3B antibody; ARP11 antibody; ARP4Actin-related protein 3B antibody; ARP3-beta antibody; Actin-like protein 3B antibody; Actin-related protein ARP4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Actin-related protein 3B protein (189-418AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P1U1 |
Uniprot Id
Q9P1U1
Target Species
Human
Target Name
ACTR3B
Target Full Name
Actin-related protein 3B
Target Function
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection.
Target Protein Families
Actin family, ARP3 subfamily
Target Tissue Specificity
Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adeno
Target Synonyms
ACTR3B; ARP11; ARP4Actin-related protein 3B; ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4
Target Background
This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.
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