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Rabbit anti-Human ADAM8 Polyclonal Antibody

The antibody against ADAM8 was raised in rabbit using the Recombinant Human Disintegrin and metalloproteinase domain-containing protein 8 protein (677-824AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-05799A

The antibody against ADAM8 was raised in rabbit using the Recombinant Human Disintegrin and metalloproteinase domain-containing protein 8 protein (677-824AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-05799A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADAM8
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Disintegrin and metalloproteinase domain-containing protein 8 protein (677-824AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP78325
Background Information
  • Uniprot Id

    P78325

  • Target Species

    Human

  • Target Name

    ADAM8

  • Target Full Name

    Disintegrin and metalloproteinase domain-containing protein 8

  • Target Function

    Possible involvement in extravasation of leukocytes.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Expressed on neutrophils and monocytes.

  • Target Synonyms

    A Disintegrin And Metalloproteinase domain 8; ADAM 8; ADAM 8 precursor; ADAM metallopeptidase domain 8; Adam8; ADAM8 protein; ADAM8_HUMAN; CD 156; CD156; CD156a; CD156a antigen; Cell surface antigen MS2; Disintegrin and metalloproteinase domain-containing protein 8; Human leukocyte differentiation antigen; Macrophage cysteine rich glycoprotein; MGC134985; MS 2; MS2

  • Target Background

    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

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