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The antibody against ADAMTSL4 was raised in rabbit using the Recombinant Human ADAMTS-like protein 4 protein (795-1074AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ADAMTSL4 was raised in rabbit using the Recombinant Human ADAMTS-like protein 4 protein (795-1074AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using ADAMTSL4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using ADAMTSL4 Antibody at dilution of 1:1002
| Cat.No | ADC-16517A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADAMTSL4 |
| Target Synonyms | ADAMTSL4 antibody; TSRC1 antibody; PP1396 antibody; UNQ2803/PRO34012ADAMTS-like protein 4 antibody; ADAMTSL-4 antibody; Thrombospondin repeat-containing protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human ADAMTS-like protein 4 protein (795-1074AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UY14 |
Uniprot Id
Q6UY14
Target Species
Human
Target Name
ADAMTSL4
Target Full Name
ADAMTS-like protein 4
Target Function
Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.
Target Involvement
Ectopia lentis 2, isolated, autosomal recessive (ECTOL2); Ectopia lentis et pupillae (ECTOLP)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix. Note=Colocalizes with FMN1 microfibrils in the eye ECM.
Target Tissue Specificity
Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta. Weaker expression in bone marrow, brain tissue, kidney and pancreas. Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lun
Target Synonyms
ADAMTSL4; TSRC1; PP1396; UNQ2803/PRO34012ADAMTS-like protein 4; ADAMTSL-4; Thrombospondin repeat-containing protein 1
Target Background
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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