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The antibody against COQ8B was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human ADCK4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against COQ8B was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human ADCK4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of HepG2 cells using ADCK4 Polyclonal Antibody
| Cat.No | ADC-39377A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COQ8B |
| Target Synonyms | COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human ADCK4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96D53 |
Uniprot Id
Q96D53
Target Species
Human
Target Name
COQ8B
Target Full Name
Atypical kinase COQ8B, mitochondrial
Target Function
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
Target Involvement
Nephrotic syndrome 9 (NPHS9)
Target Subcellular Location
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
Target Protein Families
Protein kinase superfamily, ADCK protein kinase family
Target Tissue Specificity
Widely expressed, including renal podocytes.
Target Synonyms
COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B
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