Rabbit anti-Human ADK Polyclonal Antibody

The antibody against ADK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-345 of human ADK (NP_001114.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-05307A

Number

Cat.No	ADA-05307A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ADK
Target Synonyms	AK; ADK	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-05307A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ADK

Target Synonyms

AK; ADK

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 200-345 of human ADK (NP_001114.2).	Target Species	Human
Immunogen Sequence	PFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH	Uniprot ID	P55263

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 200-345 of human ADK (NP_001114.2).

Target Species

Human

Immunogen Sequence

PFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

Uniprot ID

P55263

Background Information

Uniprot Id

P55263
Target Species

Human
Target Name

ADK
Target Full Name

Adenosine kinase
Target Function

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Target Involvement

Hypermethioninemia due to adenosine kinase deficiency (HMAKD)
Target Subcellular Location

[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.
Target Protein Families

Carbohydrate kinase PfkB family
Target Tissue Specificity

Widely expressed. Highest level in placenta, liver, muscle and kidney.
Target Synonyms

2310026J05Rik; 5033405D03Rik; Adenosine 5''-phosphotransferase; Adenosine kinase; adk; ADK_HUMAN; AI255373; AI987814; AK; MGC6593; OTTHUMP00000019864; OTTHUMP00000019865
Target Background

This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human ADK Polyclonal Antibody

Specifications

Immunogen Information

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