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The antibody against AEBP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human AEBP2 (NP_694939.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against AEBP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human AEBP2 (NP_694939.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-02529A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AEBP2 |
| Target Synonyms | AEBP2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat heart, 293T, A-549, Jurkat, Mouse skeletal muscle | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human AEBP2 (NP_694939.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6ZN18 | Immunogen Sequence |
Uniprot Id
Q6ZN18
Target Species
Human
Target Name
AEBP2
Target Full Name
Zinc finger protein AEBP2
Target Function
Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex.
Target Subcellular Location
Nucleus.
Target Protein Families
AEBP2/jing C2H2-type zinc-finger family
Target Synonyms
AEBP2; Zinc finger protein AEBP2; Adipocyte enhancer-binding protein 2; AE-binding protein 2
Target Background
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Located in nucleoplasm. Part of ESC/E(Z) complex.
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