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Rabbit anti-Human AER61 Monoclonal Antibody

The antibody against AER61 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AER61 (NP_775925.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14570A

The antibody against AER61 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AER61 (NP_775925.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-14570A ClonalityMonoclonal
Host SpeciesRabbitTarget NameAER61
Target SynonymsAOS4; AER61; EOGT1; C3orf64FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293T, HepG2, Mouse lung, Rat lung, Rat uterusApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AER61 (NP_775925.1).Target SpeciesHuman
Immunogen SequenceMLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLKYCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYUniprot IDQ5NDL2
Background Information
  • Uniprot Id

    Q5NDL2

  • Target Species

    Human

  • Target Name

    EOGT

  • Target Full Name

    EGF domain-specific O-linked N-acetylglucosamine transferase

  • Target Function

    Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.

  • Target Involvement

    Adams-Oliver syndrome 4 (AOS4)

  • Target Subcellular Location

    Endoplasmic reticulum lumen.

  • Target Protein Families

    Glycosyltransferase 61 family

  • Target Synonyms

    EOGT; AER61; C3orf64; EOGT1EGF domain-specific O-linked N-acetylglucosamine transferase; EC 2.4.1.255; Extracellular O-linked N-acetylglucosamine transferase

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