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The antibody against AGBL5 was raised in rabbit using the Fusion protein of Human AGBL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against AGBL5 was raised in rabbit using the Fusion protein of Human AGBL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-31031A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGBL5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human AGBL5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NDL9 |
Uniprot Id
Q8NDL9
Target Species
Human
Target Name
AGBL5
Target Full Name
Cytosolic carboxypeptidase-like protein 5
Target Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate. Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin. Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation.
Target Involvement
Retinitis pigmentosa 75 (RP75)
Target Subcellular Location
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody.
Target Protein Families
Peptidase M14 family
Target Tissue Specificity
Expressed in brain.
Target Synonyms
AGBL5; ATP/GTP binding protein like 5; ATP/GTP-binding protein-like 5; CBPC5_HUMAN; CCP5; Cytosolic carboxypeptidase like protein 5; Cytosolic carboxypeptidase-like protein 5; FLJ21839; Hypothetical protein FLJ21839
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