Rabbit anti-Human AGPAT2 Polyclonal Antibody

The antibody against AGPAT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 199-278 of human AGPAT2 (NP_006403.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-02984A

Number

Cat.No	ADA-02984A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	AGPAT2
Target Synonyms	BSCL; BSCL1; LPAAB; LPLAT2; 1-AGPAT2; LPAAT-beta; AGPAT2	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HT-29	Application	ELISA, WB, IF/ICC

Cat.No

ADA-02984A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

AGPAT2

Target Synonyms

BSCL; BSCL1; LPAAB; LPLAT2; 1-AGPAT2; LPAAT-beta; AGPAT2

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HT-29

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 199-278 of human AGPAT2 (NP_006403.2).	Target Species	Human
Immunogen Sequence	IVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ	Uniprot ID	O15120

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 199-278 of human AGPAT2 (NP_006403.2).

Target Species

Human

Immunogen Sequence

IVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ

Uniprot ID

O15120

Background Information

Uniprot Id

O15120
Target Species

Human
Target Name

AGPAT2
Target Full Name

1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Target Function

Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Target Involvement

Congenital generalized lipodystrophy 1 (CGL1)
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

1-acyl-sn-glycerol-3-phosphate acyltransferase family
Target Tissue Specificity

Expressed predominantly in adipose tissue, pancreas and liver.
Target Synonyms

AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1-acylglycerol-3-phosphate O-acyltransferase 2; 1-AGP acyltransferase 2; 1-AGPAT 2; Lysophosphatidic acid acyltransferase beta; LPAAT-beta
Target Background

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Rabbit anti-Human AGPAT2 Polyclonal Antibody

Specifications

Immunogen Information

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