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The antibody against AGXT was raised in rabbit using the Recombinant Human Serine--pyruvate aminotransferase protein (112-294AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against AGXT was raised in rabbit using the Recombinant Human Serine–pyruvate aminotransferase protein (112-294AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using AGXT Antibody at dilution of 1:1002
| Cat.No | ADC-08657A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGXT |
| Target Synonyms | mitochondrial antibody; Serine:pyruvate aminotransferase antibody; SPAT antibody; SPT antibody; SPYA_HUMAN antibody; TLH6 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serine--pyruvate aminotransferase protein (112-294AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P21549 |
Uniprot Id
P21549
Target Species
Human
Target Name
AGXT
Target Full Name
Alanine--glyoxylate aminotransferase
Target Involvement
Hyperoxaluria primary 1 (HP1)
Target Subcellular Location
Peroxisome. Mitochondrion.
Target Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family
Target Tissue Specificity
Liver.
Target Research Area
Signal Transduction, Metabolism
Target Synonyms
AGT; AGT1; Agxt; AGXT1; Alanine glyoxylate aminotransferase; Alanine glyoxylate aminotransferase3; Alanine--glyoxylate aminotransferase; EC 2.6.1.44; EC 2.6.1.51; Hepatic peroxisomal alanine glyoxylate aminotransferase; Hepatic peroxisomal alanine:glyoxylate aminotransferase; L alanine glyoxylate aminotransferase 1; MS773; PH1; Serine pyruvate aminotransferase; Serine--pyruvate aminotransferase; Serine--pyruvate aminotransferase, mitochondrial; Serine:pyruvate aminotransferase; SPAT; SPT; SPYA_HUMAN; TLH6
Target Background
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
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