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The antibody against AHA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-338 of human AHA1 (NP_036243.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AHA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-338 of human AHA1 (NP_036243.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01819A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AHA1 |
| Target Synonyms | p38; AHA1; hAha1; C14orf3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | COS-7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-338 of human AHA1 (NP_036243.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O95433 | Immunogen Sequence |
Uniprot Id
O95433
Target Species
Human
Target Name
AHSA1
Target Full Name
Activator of 90 kDa heat shock protein ATPase homolog 1
Target Function
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins.
Target Subcellular Location
Cytoplasm, cytosol. Endoplasmic reticulum. Note=May transiently interact with the endoplasmic reticulum.
Target Protein Families
AHA1 family
Target Tissue Specificity
Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Target Research Area
Neuroscience
Target Synonyms
Activator of 90 kDa heat shock protein ATPase homolog 1; Activator of heat shock 90kDa protein ATPase homolog 1; AHA 1; AHA1; AHSA 1; Ahsa1; AHSA1_HUMAN; C14orf3; HSPC322; p38
Target Background
Enables ATPase activator activity; Hsp90 protein binding activity; and chaperone binding activity. Involved in positive regulation of ATPase activity. Located in cytosol.
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