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Rabbit anti-Human AHSP Polyclonal Antibody

The antibody against AHSP was raised in rabbit using the Recombinant Human Alpha-hemoglobin-stabilizing protein (1-102AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-40289A

The antibody against AHSP was raised in rabbit using the Recombinant Human Alpha-hemoglobin-stabilizing protein (1-102AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-40289A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAHSP
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Alpha-hemoglobin-stabilizing protein (1-102AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NZD4
Background Information
  • Uniprot Id

    Q9NZD4

  • Target Species

    Human

  • Target Name

    AHSP

  • Target Full Name

    Alpha-hemoglobin-stabilizing protein

  • Target Function

    Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    AHSP family

  • Target Tissue Specificity

    Expressed in blood and bone marrow.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    AHSP; AHSP_HUMAN; Alpha hemoglobin stabilizing protein; Alpha-hemoglobin-stabilizing protein; EDRF; ERAF; Erythroid associated factor; Erythroid differentiation associated factor; Erythroid differentiation related factor; Erythroid differentiation-related factor; Erythroid-associated factor

  • Target Background

    This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants.

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