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The antibody against AIFM3 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human AIFL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against AIFM3 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human AIFL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of HeLa cells using AIFL Polyclonal Antibody
| Cat.No | ADC-39365A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AIFM3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human AIFL. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96NN9 |
Uniprot Id
Q96NN9
Target Species
Human
Target Name
AIFM3
Target Full Name
Apoptosis-inducing factor 3
Target Function
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Target Subcellular Location
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Target Protein Families
FAD-dependent oxidoreductase family
Target Tissue Specificity
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Target Synonyms
AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor; mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137
Target Background
Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; flavin adenine dinucleotide binding activity; and metal ion binding activity. Involved in execution phase of apoptosis. Located in cytosol; endoplasmic reticulum; and mitochondrial inner membrane.
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