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The antibody against AKAP7 was raised in rabbit using the Recombinant Human A-kinase anchor protein 7 isoforms alpha and beta protein (1-81AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against AKAP7 was raised in rabbit using the Recombinant Human A-kinase anchor protein 7 isoforms alpha and beta protein (1-81AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AKAP7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using AKAP7 Antibody at dilution of 1:1002
| Cat.No | ADC-25273A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AKAP7 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human A-kinase anchor protein 7 isoforms alpha and beta protein (1-81AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43687 |
Uniprot Id
O43687
Target Species
Human
Target Name
AKAP7
Target Full Name
A-kinase anchor protein 7 isoforms alpha and beta
Target Function
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
Target Subcellular Location
[Isoform Alpha]: Lateral cell membrane; Lipid-anchor. Note=Targeted predominantly to the lateral membrane.; [Isoform Beta]: Apical cell membrane; Lipid-anchor. Note=Targeted predominantly to the apical membrane.
Target Tissue Specificity
Expressed in brain, heart, lung, pancreas and skeletal muscle.
Target Synonyms
A kinase (PRKA) anchor protein 7; A kinase anchor protein 18 kD; A kinase anchor protein 7; A kinase anchor protein 7 isoform alpha; A kinase anchor protein 7 isoform beta; A kinase anchor protein 7 isoform gamma; A kinase anchor protein 7 isoforms alpha and beta; A kinase anchor protein 9 kDa; A kinase anchoring protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoforms alpha and beta; AKA7A_HUMAN; AKAP 18; AKAP 7; AKAP-7 isoforms alpha and beta; AKAP15; AKAP18; Akap7; HGNC377; OTTHUMP00000040266; Protein kinase A anchoring protein 7; Protein kinase A anchoring protein 7 isoform alpha; Protein kinase A anchoring protein 7 isoform beta; Protein kinase A anchoring protein 7 isoform gamma; Protein kinase A anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta
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