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The antibody against AKIP1 was raised in rabbit using the Recombinant Human A-kinase-interacting protein 1 protein (57-167AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against AKIP1 was raised in rabbit using the Recombinant Human A-kinase-interacting protein 1 protein (57-167AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using AKIP1 Antibody at dilution of 1:100
| Cat.No | ADC-08148A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AKIP1 |
| Target Synonyms | AKIP1 antibody; BCA3 antibody; C11orf17A-kinase-interacting protein 1 antibody; Breast cancer-associated gene 3 protein antibody; PKA-interacting protein antibody; Proline-rich protein BCA3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human A-kinase-interacting protein 1 protein (57-167AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NQ31 |
Uniprot Id
Q9NQ31
Target Species
Human
Target Name
AKIP1
Target Full Name
A-kinase-interacting protein 1
Target Function
Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.
Target Subcellular Location
Nucleus. Note=Locates to punctate spots.
Target Tissue Specificity
Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
Target Synonyms
AKIP1; BCA3; C11orf17A-kinase-interacting protein 1; Breast cancer-associated gene 3 protein; PKA-interacting protein; Proline-rich protein BCA3
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