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The antibody against AKR7A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AKR7A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00024A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AKR7A3 |
| Target Synonyms | AFAR2; AKR7A3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, HepG2, HT-29, Mouse liver, Mouse pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O95154 | Immunogen Sequence |
Uniprot Id
O95154
Target Species
Human
Target Name
AKR7A3
Target Full Name
Aflatoxin B1 aldehyde reductase member 3
Target Function
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Aldo/keto reductase family, Aldo/keto reductase 2 subfamily
Target Tissue Specificity
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Target Research Area
Signal Transduction
Target Synonyms
AFAR 2; AFAR2; AFB1 aldehyde reductase 2; AFB1 AR 2; AFB1-AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Akr7a3; Aldo keto reductase family 7 member A3; ARK73_HUMAN; OTTHUMP00000002623
Target Background
Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.
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