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Rabbit anti-Human AKR7A3 Polyclonal Antibody

The antibody against AKR7A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00024A

The antibody against AKR7A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00024A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAKR7A3
Target SynonymsAFAR2; AKR7A3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, HepG2, HT-29, Mouse liver, Mouse pancreasApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human AKR7A3 (NP_036199.2).Target SpeciesHuman
Uniprot IDO95154Immunogen Sequence
Background Information
  • Uniprot Id

    O95154

  • Target Species

    Human

  • Target Name

    AKR7A3

  • Target Full Name

    Aflatoxin B1 aldehyde reductase member 3

  • Target Function

    Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Aldo/keto reductase family, Aldo/keto reductase 2 subfamily

  • Target Tissue Specificity

    Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    AFAR 2; AFAR2; AFB1 aldehyde reductase 2; AFB1 AR 2; AFB1-AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Akr7a3; Aldo keto reductase family 7 member A3; ARK73_HUMAN; OTTHUMP00000002623

  • Target Background

    Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.

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